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The sequential optimizations of experimental conditions till Eq. (6) is validated for each pair of a quantifiable candidate ligand from a mixture sample and a suitable reference ligand will ultimately give the relative affinity of every quantifiable candidate ligand in the mixture sample.
It is laborious to optimize experimental conditions till Eq. (6) is validated for each pair of a quantifiable candidate ligand from a mixture sample and a suitable reference ligand, when candidate ligands in such a mixture sample have a large number or large differences in their quantities.
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The reverse CV scan of the cathodic wave was validated for each concentration as demonstrated in the supporting information (Fig. S2).
Therefore, use of an image-derived input function (IDIF) can be an interesting alternative [18 20], but its utility needs to be validated for each tracer, each scanner, and each acquisition and data analysis protocol separately.
Simulator performance shows medium to strong correlations with many on-road driving performance measures as well as to cognitive and physiological measures, however simulators need to be validated for each new setting [32].
However, one must realize that the usefulness of our method must be validated for each radioligand because determination of the arterial input function based on the left ventricle could lead to a poor resemblance with the blood sampling input curve especially for radioligands with high myocardial uptake.
Therefore, it is imperative that all reference genes are validated for each experimental condition regardless of whether a single reference gene or the geometric mean of multiple reference genes is the chosen method of normalization.
The proportional hazards assumption was validated for each model.
The reproducibility of results must be validated for each measurement.
These were validated for each individual and across all interviews in discussion with the second author.
Based on medical record abstraction, SLE classification criteria were validated for each individual.
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