Bao et al. identified 147 out-of-frame fusions that were not followed up for validation.
I recently participated in a standards validation committee for the Arizona Department of Education to make sure learning requirements for students in sales and marketing were up to date and correct.
The best concordant rates were with the SAM survival analysis, wherein of the 11 genes taken up for validation, 8 were concordant (73%).
What's more, Blanchett, Mara and Redmayne are all up for Oscars: what validation for queers like me.
You say that you know that this woman is looking for validation.
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Genetic studies (in particular linkage and association studies) identify chromosomal regions involved in a disease or phenotype of interest, but those regions often contain many candidate genes, only a few of which can be followed-up for biological validation.
Most folks, myself included, were -- are -- looking for validation.
In our study, several DEGs were picked up for RT-qPCR validation, such as DPT, COMP, and COL10A1.
The investigation focuses on the 2011 Tohoku tsunami because rich datasets from global positioning system (GPS), ocean bottom pressure gauges, tidal measurements, and tsunami inundation/run-up survey results are available for validation of tsunami simulations (Fujii et al.2011; Maeda et al.2011; Mori et al.2011,2012; Ozawa et al.2011; Goto et al.2012; Kawai et al.2013).2013
All coding substitution variants and a random assortment of noncoding variants were selected for validation to make up to ∼400 PCR products per sample.
