Immunoblot analysis showed accumulation of the unprocessed form of Rap1 in all cell lines exposed to lovastatin for 24 hours, indicating that drug uptake was universally achieved.
The new SLICC classification criteria with better sensitivity will probably help in better identification of patients, but we have not yet reached the stage where early diagnosis can be universally achieved.
Current UK recommendations aim to reach an HbA1c level of 6.5% (equivalent to 48 mmol/mol) or 7.5% (equivalent to 59 mmol/mol) for those at risk of severe hypoglycaemia, although these targets are not intended to be universally achieved [ 5].
It is therefore recommended that the IS approach be universally adopted to achieve deep energy savings.
The need for collaboration and compromise in a dynamic aid system is universally recognised, and is frequently achieved through active contribution by aid workers to their organisational programmes and directives.
Moreover, even if commitments are fulfilled, the total will still fall far short of the $100bn£63bnbn) a year that is universally recognised as necessary to achieve the millennium development goals.
PAINTING and dancing have this advantage over the other arts, that they are of every country, of all nations, that their language is universally understood, and that they achieve the same impression everywhere," wrote the 18th-century ballet master and dance theorist Jean Georges Noverre in "Lettres sur la Danse et les Ballets".
True restoration of highly disrupted native ecosystems is universally difficult, and has not been achieved on waste rock dumps at a rock phosphate mine in the resource-limited rangeland environment of semi-arid Queensland, Australia.
This is mainly to achieve a staging system that is universally available and as cervical cancer is more prevalent in developing countries, only clinical methods are universally available.
To achieve these ambitious objectives it is universally recognized we must reduce malaria transmission through the mosquito vectors.
