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While neither element is uniquely essential for promoter function, the correlation of the development of these promoter elements with the appearance of PDE4D6 ESTs suggests sequence drift in the promoter region is responsible for transcription of this splice variant in mammals more derived than M. domestica.
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One intracellular adaptor, talin, is particularly critical for this connection, being uniquely essential for all integrin adhesive functions within developing organisms [ 3, 4].
Our multidisciplinary strategy of cell, molecular and chemical biology, mouse and human genetics, medicinal chemistry and computational modeling is uniquely suited to walk the essential pathway from compound discovery to preclinical validation of new therapies.
And given its bounty of essential nutrients, it is uniquely suited for lifelong sustenance.
The requirement that the main equation is uniquely solvable (Condition S in Theorem 6) is essential and cannot be omitted (see Example 1.6.1 in [2]).
Additionally, we cannot conclude that the ApoE−/− mouse is uniquely susceptible to CO, and comparative exposures with other strains/species is essential for proper context.
His advisers say that by virtue of his background Mr. Kerry is uniquely suited to re-establish the Democratic Party's credibility on national security, an essential threshold for any challenger after Sept. 11, 2001.
"It is uniquely challenging".
This is uniquely confusing".
LDMDCP is uniquely brilliant.
But Japan is uniquely Japanese.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com