Exact(16)
Given that GBM is typically localized in one lobe, seldom metastasizes, and exhibits local recurrence, the disease is a proper candidate for local treatments.
The resulting damage is typically localized at the above ground portion of concrete members.
Unlike acne vulgaris, rosacea is typically localized commonly over the central face (i.e. medial cheek, nose, forehead, and chin).
In contrast, RGS14 is typically localized to the cytosol, nucleus, and perinuclear regions in interphase, and on microtubule structures during mitosis [53] [55].
Tau, encoded by MAPT, is typically localized to axons where it binds and stabilizes microtubules.
In healthy motor neurons, TDP-43 is typically localized to the nucleus.
Similar(44)
Cardiovascular disease processes such as atherosclerosis, restenosis, and inflammation are typically localized to discrete regions of the vasculature, affording great opportunity for targeted pharmacological treatment.
These cells were typically localized in the center of grafts and were DCX-negative (Fig. 4H).
One class showed irregularly sized foci that were typically localized near each cell pole or randomly positioned within the cell (Figure 3A, Figure S1).
Mature miRNAs hybridize to partially complementary binding sites that are typically localized in the 3' untranslated regions (3'UTR) of target mRNAs [29].
However, except for instances where distal regions were targeted with viral vectors (e.g., AAV vectors) capable axonal transport, correction of lysosomal storage pathology was typically localized to areas that were proximal to the injection site.
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