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The global tendency for ChIP-Seq data to yield motifs for the ChIP'd TF proximal to the peakMax is systematically confirmed here with a study of ~340 ChIP-Seq datasets for ~95 TFs (human and mouse).
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Each positive slide was systematically confirmed by all three senior microscopists.
First, the synchronization of experimental cultures by age and growth stage was systematically confirmed by protein quantification and fluorescence microscopy.
Species identification was systematically confirmed by sequencing the rrs gene.
For all of the assays, when an amplified product was detected, T. whipplei was systematically confirmed by sequencing, as previously reported [ 19].
If a first PCR assay was positive, the result was systematically confirmed by a second PCR assay using a second set of primer pairs.
The identification was systematically confirmed by manual interpretation of the MS/MS spectra by the "peptide sequence tag" method using the BioAnalyst and PeptideSearch softwares (www.narrador.emblheidelberg.de) (20, 21).
Presumably, these policy changes have significantly contributed to a reduction in malaria burden and hospital admissions; however, caution should be exercised before generalizing these trends to the whole country because these findings have not been systematically confirmed in remote rural provinces of Gabon.
The morbidity of malaria has steady declined in the urban regions of Gabon between 2000 and 2008, but caution should be exercised before generalizing this trend to the whole country because this finding has not been systematically confirmed in remote rural provinces.
On the assumption that brain lesions are transiently associated with decreased extracellular Mg2+ concentration, even if this observation has not been systematically confirmed in humans, Mg2+ solution infusion was tested and was found to worsen the outcome in patients with traumatic brain lesions.
Postoperative pneumonia was systematically confirmed by microbiologic analysis using bronchoalveolar lavage with fiberoptic bronchoscopy (yielding bacteria at a concentration of >10 colony forming units (CFU /mL) or blind protected distal bronchial specimen samples (yielding >10 CFU/mL) or blind endotracheal aspiration (yielding >10 CFU/mL).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com