Sentence examples for is sufficient to transform from inspiring English sources

In contrast to the transformation of HMEC-DD cells, one oncogenic event is sufficient to transform Rat1-DD cells, indicated by both anchorage-independent growth in vitro and tumor formation in vivo (Ni et al., 2012).

In contrast to the transformation of HMEC-DD cells, one oncogenic event is sufficient to transform Rat1 rodent fibroblasts expressing p53DD (Rat1-DD) cells, as indicated by both anchorage-independent growth in vitro and tumor formation in vivo (Ni et al., 2012).

The Commissions' enforcement actions are based on the theory that the manipulative intent of the trader is sufficient to transform otherwise legitimate transactions into open-market manipulation.

Furthermore, overexpression of wild-type NSD2 is sufficient to transform NSD2-/ cancer cells in vivo and in mouse embryonic fibroblasts (MEFs) (Kuo et al., 2011).

Whether the use of a gmail account instead of one's official dot-gov account is sufficient to transform otherwise public records -- records that belong to the people -- into the personal property of government officials, will be decided soon by the Third District Court of Appeal.

Our results using IHC provide novel insights that support the contention that MYC overexpression is sufficient to transform prostate luminal epithelial cells into PIN cells in vivo.

A single nucleotide change can be sufficient to transform a proto-oncogene into an oncogene that induces cell transformation, whereas an inhibiting mutation must affect the two alleles of a tumor suppressor gene to favor transformation [ 61].

This temperature was sufficient to transform all volatile chlorine, which amounts to 15% of total coal chlorine, to the gas phase.

A freak inch of snow was sufficient to transform the brawny midfielder into the proverbial elephant on ice skates.

Finally we validated our key findings in a small series of DSRCT.Neither isoform of EWS/WT1 was sufficient to transform wild-type MEFs however the oncogenic potential of both was unmasked by p53 loss.

Although mutant PIK3CA has been reported to be sufficient to transform normal cells both in vitro [44], [45], [46] and in vivo [46], [47], PIK3CA mutation exhibits a relatively low frequency in ovarian cancer (4.8 12%) [28], [29], [30], [32] as compared to other cancer types.