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The advantage of such a piece is that spacing between letters, even the letter forms themselves, can be subtly modified.
This understanding was subtly modified by Thoreau's mentor, Emerson, who agreed that the world was a manifestation of spirit — "Every natural fact is a symbol of some spiritual fact," he wrote — but believed natural facts had only a latent meaning until they were perceived by a human observer.
To do that, we notice that some of the definitions involved in the last theorem were subtly modified in [17] in the following sense.
In the above test when cutting and pasting from an HTML page into WordPad you'll notice that the accounts are subtly modified in each case while leaving the beginning of the address unchanged.
Key roles for residues conserved between bacterial and eukaryotic homologues suggest a conserved mechanism of peptide recognition and transport that in some cases has been subtly modified in individual species.
In addition the inserts of the BACs can be subtly modified to include reporter genes or point mutations using homologous recombination in E. coli mediated by RecA [ 1- 3], the RecET system [ 4- 7] or the Red system (Redα/Redβ or exo/ bet)[ 8, 9].
Update: As comments below note, this actually is quite useful when you're subtly modifying the same search query to get even more specific.
It is subtly lighted.
But something in him is subtly different.
Shiro, seasoned chickpea stew, is subtly sweet.
The effect is subtly intoxicating.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com