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Justyna Jupowicz-Kozak quote

Justyna Jupowicz-Kozak

CEO of Professional Science Editing for Scientists @ prosciediting.com

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is substantially unknown

Grammar usage guide and real-world examples

USAGE SUMMARY

The phrase "is substantially unknown" is correct and usable in written English.
It can be used to describe something that is largely not known or understood, often in a formal or academic context. Example: "The origins of the ancient artifact are substantially unknown, leading to much speculation among historians."

✓ Grammatically correct

Science

News & Media

Human-verified examples from authoritative sources

Exact Expressions

1 human-written examples

Indeed, although randomized clinical trials have demonstrated survival benefits associated with the use of adjuvant treatments, depending on the type and duration of therapy, the age of the patients, and the characteristics of the tumour [ 1], the extent to which these benefits translate to the population outside the controlled conditions of clinical trials is substantially unknown.

Science

BMC Cancer

Human-verified similar examples from authoritative sources

Similar Expressions

59 human-written examples

Along with Abi2, the 85 functional genes may be the most important group to investigate alternative splicings, since they are substantially unknown in neural cells or organs.

Science

Plosone

The NMR interaction graph G constructed from NMR data is substantially corrupted from G*, and has an unknown vertex correspondence.

Now, it is substantially unchanged.

News & Media

The New York Times

"The operation is substantially complete.

News & Media

The Guardian

And practice is substantially heritable").

News & Media

The New Yorker

Finance is substantially about controlling risk.

News & Media

The New York Times

Maybe there is substantially more.

News & Media

Forbes

Adjusted for inflation, it is substantially lower.

News & Media

Forbes

While the biochemical mechanisms underlying arsenicosis are still substantially unknown, arsenic is a known carcinogen; there is extensive literature that links human exposure to inorganic arsenic with a variety of cancers, including lung cancers, skin cancers, and urinary bladder carcinoma.

The hazardous effects of smokeless tobacco on health in many low and middle-income countries are, however, substantially unknown.

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Expert writing Tips

Best practice

Use "is substantially unknown" when you want to convey a significant lack of knowledge or understanding about a subject. It's suitable for academic, scientific, or formal writing where precision is important.

Common error

Avoid using "is substantially unknown" in casual conversation or informal writing. Simpler phrases like "we don't know much about it" or "it's not well understood" are more appropriate.

Antonio Rotolo, PhD - Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Antonio Rotolo, PhD

Digital Humanist | Computational Linguist | CEO @Ludwig.guru

Source & Trust

86%

Authority and reliability

4.1/5

Expert rating

Real-world application tested

Linguistic Context

The phrase "is substantially unknown" functions as a predicate adjective, modifying the subject of a sentence by describing its state of being not well-known or understood. As Ludwig AI confirms, it describes something that is largely not known or understood.

Expression frequency: Uncommon

Frequent in

Science

41%

News & Media

30%

Academia

6%

Less common in

Encyclopedias

4%

Wiki

3%

Formal & Business

3%

Ludwig's WRAP-UP

In summary, the phrase "is substantially unknown" is a grammatically correct and usable expression employed to indicate a significant lack of knowledge or understanding about a particular topic. Ludwig AI states that the phrase can be used to describe something that is largely not known or understood. While it appears most frequently in scientific and news-related contexts, its formal register makes it less suitable for casual conversation. Alternatives such as "is largely unstudied" or "remains largely a mystery" can be used depending on the specific nuance you want to convey. Remember to use this phrase judiciously, opting for simpler language in informal settings.

FAQs

How can I use "is substantially unknown" in a sentence?

You can use "is substantially unknown" to describe topics where knowledge is lacking. For example: "The long-term effects of the treatment "are substantially unknown" for children".

What are some alternatives to "is substantially unknown"?

Alternatives include "is largely unstudied", "remains largely a mystery", or "is mostly unexplored". The best choice depends on the specific context.

Is it better to say "is substantially unknown" or "is completely unknown"?

"Is substantially unknown" implies a significant lack of knowledge, but not necessarily a complete absence of it. "Is completely unknown" suggests that nothing is known. The choice depends on the degree of uncertainty you want to convey.

In what contexts is "is substantially unknown" most appropriate?

"Is substantially unknown" is most appropriate in formal and scientific writing when discussing topics where information is limited or uncertain. It's less suitable for informal conversation.

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Source & Trust

86%

Authority and reliability

4.1/5

Expert rating

Real-world application tested

Most frequent sentences: