Sentence examples for is substantially involved from inspiring English sources

Among the above mechanisms, we assume that the medulla is substantially involved as a hub structure related to interictal WPH, because similar brainstem volume reduction and structural alteration [75, 76] were observed in migraine and FM, and it includes the serotonergic system from the rostral ventromedial medulla, which has been implicated in migraine and FM pathophysiology [80].

Taken together, these results indicate that Rho-kinase is substantially involved in the myocardial remodeling after TAC and MI associated with upregulation of profibrotic gene expression and TGF-β1 TAK1 paTGF-β1 TAK1her suggest the pathwayive efurtherf fasuggestn hearthegainst protectiveal stimuli by inhibiting reffecte fibrofis.

Recent studies of functional and effective brain connectivity in nonimpaired readers suggest that the left OT cortex is substantially involved in driving brain activation in left inferior frontal areas (e.g., [51] [54]).

Recent data in mice as well as in humans demonstrate that PD-1 is substantially involved in the control of T-cell homeostasis under physiological and pathological conditions [26] by preventing uncontrolled proliferation of autoreactive T-cells [27].

Moreover, ROCK is substantially involved in the pathogenesis of coronary vasospasm, angina pectoris, hypertension, pulmonary hypertension, and heart failure [ 38].

Direct assays of oxidant induced cell death indicate that most 'free' iron is concentrated in lysosomes [ 1574- 1577], that its decompartmentation is substantially involved [ 1570], and that its chelation can thus prevent cell death [ 1578 - 1581]

DJ made substantial contributions to the conception and design of this study and was substantially involved in the acquisition, analysis and interpretation of data.

The union, Mr. Lhota charged in the letter, "was substantially involved" in his appointment.

Ethics rules bar Mr. Pitt from ever participating in any matter in which he had been substantially involved when he was in private practice.

"As an appointed special prosecutor, Don will be an integral member of our team, who will review this case with me and be substantially involved in our decision".

The Department of Justice in Washington is likely to be substantially involved in any decision to indict because the case is so sensitive and high profile".