It is substantially harder for smaller sites to break through the noise.
Sorry, son, I can't help you with that PlayStation VR headset that's got itself somehow wedged somewhere it shouldn't be, daddy's at the end of Kid Icarus and this gigantic-eyed wall-cum-mythical-monster boss is substantially harder than muscle memory is willing to remember.
The same assessment is substantially harder for images of vitrified specimens, where the poor SNR of the images can make it difficult to even see the particle.
It is possible to electrocute enemies in water with the trap bolt from your crossbow, although this is not available until much later in the game and is substantially harder and more costly to perform.
It is shown that even though the contributions of the cross couplings are usually insignificant, they may become important if the vibration isolators are substantially hard as compared with the local shell stiffness or impedance.
However, nanoindentation showed that the wear track was substantially harder than the base metal.
These small issues raise concerns that reaching agreement on large politically risky issues will be substantially harder.
"Nationwide events like this would be substantially harder to build if you had to pay to get the message to people who care".
Participants were faster on average in the single-cue condition (M = 884 ms, SD = 198 ms) than in the three-cue condition (M = 1,166 ms, SD = 295 ms), indicating that, as intended, the three-arrow cue was substantially harder to process than the single-arrow cue.
It is remarkable that the composite is substantially stronger and harder than each constituent phase individually.
This figure is substantially lower than the hard data on the number of foreign-trained doctors and nurses working in the Canadian health care system, but could be a result of our focus on HHR employed by public health authorities and not those working in publicly-financed but privately-run practices.
