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For example, the last occurrence of Stylacontalium aquilonaris, which is widely recognized in the Pacific at 0.33 Ma (Matsuzaki et al. 2015b), is substantially earlier in the Japan Sea.
This is substantially earlier than the previously first described NG-MAST ST1407 strain, which possessed the mosaic PBP 2 XXXIV, identified in the USA in 2008 [ 30].
20 PTX3 levels peak at about 7 h after acute MI, which is substantially earlier than CRP, and thus PTX3 could be a better independent predictor of CHD than CRP.
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Molecular clock estimates showed that the timing of divergence in Joshua tree was substantially earlier than in the moths, rejecting the hypothesis that a common vicariant event caused the divisions within these species.
In addition, serially tracking the transcript abundance of p16INK4A and p21CIP1 revealed population doubling-dependent upregulation of both senescence biomarkers was substantially earlier in SMCs on Col1a1 r/r collagen vs. SMCs on wild-type collagen (P < 0.001, Fig. 4D).
An appropriate match could not be located for 1,119 of the eligible cases because the date of birth of these cases (mean year of birth 1947.99; range 1901 to 1981) was substantially earlier compared to the pool of remaining controls (mean year of birth 1966.57; range 1903 to 1989).
The current estimate of prevalence is approximately 1∶110 [3], which is substantially higher than earlier estimates [4].
The sensitivity is substantially increased compared with earlier designs.
The total value is "substantially more" than an earlier government estimate of $150 million, officials said.
It is substantially higher than an earlier reported national figure of 171/100,000 for Pakistan [ 8].
Prognosis for oral cancer is substantially improved when diagnosed early.
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