Sentence examples for is substantial to both from inspiring English sources

4 Despite notably reduced incidence and mortality rates, the burden of cervical cancer precursor lesions and the disease is substantial to both social and health care paradigms.

When the Manchester scale scores were dichotomised, agreement was substantial to almost perfect for both re-test comparisons (kappa = 0.80 to 0.89) and substantial for comparisons between participants and examiners (kappa = 0.64 to 0.76).

Given the significant challenges associated with adding a writing course into an already packed curriculum, the payoffs need to be substantial to justify the effort by both faculty and students.

However, the importance of social factors in depression is undeniable, and there is substantial evidence to suggest that both onset and recovery are related to life events and difficulties.

Although most people with type 2 diabetes will need insulin therapy to maintain A1C <7.0% 9 years after diagnosis (37), there is substantial resistance to its introduction, both from patients (45) and physicians (46).

There is substantial evidence to indicate that both investigators and patients can distinguish between active treatment and placebo in double blind studies.

Again, there is substantial evidence that both the risk to health and the addictive nature of tobacco are underestimated [ 48].

Lost productivity due to CFS was substantial both on an individual basis and relative to national estimates for other major illnesses.

Although there is evidence for inter-paralog gene conversion for the GOT1Sd and GOT1Sr paralogs as well, it does not appear to have been substantial enough to result in both copies retaining their open reading frames in all haplotypes.

"There are substantial risks to the outlook in both directions," the bank's governor, Mervyn A. King, left, said.

However, there was substantial variability due to both the small number of patients who had a recurrence and the limited information available on these cases.