Sentence examples for is substantial impact from inspiring English sources

In contrast, although we generally agree that there is substantial impact of non-genetic factors on the etiology of ALS, so far little progress has been made in identifying these factors with some degree of certainty.

The burden of disease associated with PD is substantial, impacting on individuals, the healthcare system and society [ 4].

To the extent that this change in susceptibility were substantial, impact estimates might be biased.

Furthermore, disease-modifying effects of bipolar disorder and diabetes mellitus on each other appear to be substantial, impacting both treatment response and outcomes.

It should be noted that this is substantial negative impact on exports even in comparison with the likely positive impact of the FTA/NAFTA, which, even though it reduced non-tariff barriers, only eliminated tariffs averaging around one per cent.

Overall, the burden of foot disease in RA is substantial and impacts negatively on health-related quality of life [ 4, 6].

At the same time, the shake-up required is substantial, and the impact on advertiser-supported media a concern.

The climate impact is substantial.

Some of the norms he is violating appear minor, but their collective impact is substantial.

Although the domain of interest is quite narrow, the impact is substantial, particularly in comparison with that shown in Fig. 5e.

The potential impact is substantial given the extensive use of mammalian expression systems in research and manufacturing of protein biotherapeutics.