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We have reported previously that cholinergic modulation in V1 of the macaque monkey is strongly targeted toward GABAergic interneurons.
Moxifloxacin has beneficial pharmacokinetic and pharmacodynamic properties, is strongly targeted to alveolar tissue, and demonstrates rapid initial killing with high eradication rates [ 48].
Moxifloxacin is strongly targeted to alveolar tissue [ 18, 19] and demonstrates rapid initial killing and eradication rates for pneumococcal bacteria [ 16].
This sort of epistasis would depress the rate of substitution at a site, reducing the signal in a dN/dS test even if a site is strongly targeted by CTLs.
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Adam Voges will begin the season - David Hussey will end it - with a nice coming together in the middle as both Aussies will participate in the FPt20 - another piece of silverware being strongly targeted this year.
Oxidative coupling, wherein higher hydrocarbons (specifically ethylene) are generated has been strongly targeted [4], as has direct partial oxidation to yield methanol or formaldehyde in a single step [5].
The ksI24 30 EGFP), containing only the 24RKRNRSP30 NLS motif of Region I, was strongly targeted to the nucleus (Fig. 2B) and gave a very distinct accumulation in specific nuclear spots, characteristic of nucleoli (arrow, Fig. 2B).
The RNase L ankyrin repeats domain was strongly targeted by selection, as well.
The biological processes of amino acid metabolism, precursor generation and carbohydrate metabolism are strongly targeted.
These puncta are strongly targeted to the distal thylakoids (Fig. 1H, L and P, 3W).
Analysis of the PRRs underscored major signatures of adaptive evolution for cGAS in both Chiroptera and Primates, whereas OAS1 was strongly targeted by selection in Primates, and much more weakly in bats.
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