Translocation of nanoparticles through the alveolar barrier, if it takes place, has been speculated to depend primarily on endocytotic-exocytotic activity and less so by paracellular transport e.g., due to histamine, hydrogen peroxide [13].
A rationale is provided wherein chemical resistance is speculated to be operative.
Although offshore tsunami deposits were speculated to be more common than onshore deposits (Dawson and Stewart, 2007), their actual deposition and subsequent preservation depends strongly on the local geomorpholog-ical configurations of the shelf and nearshore area and onshore conditions.
This thin layer was speculated to be natural tungsten oxide.
In this respect, it can be speculated that depending on the epigenetic state of chromatin in the target locus, different functional domains fused to ZFs may exhibit various efficacies.
The emulsification seems to be therefore time dependent [ 11] and it has been speculated that it depends on a combination of the saccadic motion, the difference in density of intraocular fluids and silicone oil, and the gradual decrease of interfacial surface tension of the oil due to the adsorption of surface-active components from the intraocular fluids [ 3, 8, 9].
It may be speculated that such results depend on additional factors such as therapeutic area, patient age or education level, number of medications or general healthcare context.
More than seventy years ago, it was speculated that antibody binding depends on unfolded rather than structured protein [ 1, 2].
It can be speculated that maintenance of CSCs depends upon a specific stem cell niche microenvironment that protects CSCs from therapeutics.
