Sentence examples for is specifically mediated from inspiring English sources

It is also clear that RBC necroptosis induced by hCD59-specific PFTs is specifically mediated by endogenous FasL and not TNF- α or TRAIL.

Collectively, our data suggest that the deubiquitination of ANXA1 is specifically mediated by HAUSP, and HAUSP-mediated deubiquitination of ANXA1 may be important for ANXA1's damage response function in the nucleus upon UV.

These data demonstrate that the ubiquitination of p62 is specifically mediated by parkin, while the disease causing mutants that have impaired E3 ligase activity fail to ubiquiniate p62 for its subsequent degradation (Fig. 5F).

Taken together, our results demonstrate that complement activation on immobilized acBSA under the described assay conditions is specifically mediated by Ficolin-3.

In contrast, HUVECs did not affect the viability of CD34+ cells (n = 6, P>0.05) (Fig. 4C), indicating that the pro-survival effect is specifically mediated by CD34+-derived ECs.

But failure to observe similar splicing phenotype associated with either over expression or depletion of another SR protein, dASF, further supports the idea that eyeless alternative splicing is specifically mediated by direct interaction of B52 with exon 2 sequences.

It would be important to dissect which domain or which KLF4 zinc finger is specifically mediating the interaction with un-methylated DNA.

Additionally, the outcome of a directed yeast two-hybrid assay identify importin α6 as a specific partner of BRMS1 thus speculating that BRMS1 nuclear import could be specifically mediated by the reported nuclear transporter.

Moreover, the E2 effect in these cells was specifically mediated by ER α as deduced by the effect of the specific ER α agonist 4,4′,4′′- 4-propyl- 1H -pyrazole-1,3,5-triyl) trisphenol (PPT) or the specific ER β agonist 2,3-bis(4,4′,4′′- 4-propyl- 1H -pyrazole-1,3,5-triyl

However, the horizontal transfer of SGI1 was shown to be specifically mediated by conjugative helper plasmids of the broad-host-range IncA/C incompatibility group.

To confirm that the antibody-stimulation of cell growth was specifically mediated by MUC1, the experiments were repeated using MUC1-positive breast cancer cells, T47Ds, that had been stably transfected with siRNA to knockdown MUC1 expression.