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These results demonstrate that the attenuated virulence phenotype of KKF332 is specifically dependent upon loss of FopC.
This modulation is specifically dependent upon the characteristics of the sniffed smell, being maximal with olfactory-gustative stimuli and absent with trigeminal ones.
The precise developmental relationship of the cell lineages in the human pancreas remains uncertain, but in mice the generation of β-cells is specifically dependent upon the transcription factor Pax4. Inactivation of Pax4 by homologous recombination resulted in the absence of mature insulin-producing β-cells in the pancreas of Pax4 homozygous mutant mice [14].
The significance of alternative transcripts derived from alternative splicing could be tested by disrupting reporter expression that is specifically dependent upon translation across the optional protein-coding region.
Similar to other groups we have found that NK cells can be a source of MIP-1 α; however, its release is specifically dependent upon the activity of GrzM.
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Downregulation of PLCγ1 expression using specific siRNA significantly reduced the FGF-2-dependent production of inositol phosphates, indicating that this isoform is specifically activated upon FGF-2 stimulation (Figure 1A).
ARF is specifically expressed upon injury.
NF-Y is specifically required for genes regulated during the cell-cycle, and inducible by external stimuli: essentially all G2/M genes, for example, are dependent upon NF-Y [21], [28].
We observed a global decrease of trimethylated Lys 27 (H3K27me3), but not of trimethylated Lys 4 (H3K4me3) at day 3 post-EZH2 siRNA transfection, suggesting that EZH2-dependent histone methylation was specifically impaired upon EZH2 siRNA.
Three individuals enter and are specifically focused upon during entry.
Therefore, it is possible that the synergistic effect of CCM+DHA on SK-BR-3 cells is dependent specifically upon CCM uptake ability of this cell line, as opposed to its cellular receptor expression state, but further study of this distinction must account for the unique transcript-level regulation observed in the presence of CCM+DHA and not CCM alone.
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