Sentence examples for is specifically deleted from inspiring English sources
This finding further confirms that in the CKO mice, β-catenin is specifically deleted in the mesenchyme but importantly, it also demonstrates that mesenchymal β-catenin signaling at E13.5 does not rely primarily on LEF1/TCF transcription factors.
However, further studies will be required to definitively determine if these VHL-associated pancreatic manifestations can be recapitulated when Vhl is specifically deleted in progenitor cells of ductal, exocrine or endocrine lineage.
The genomic region encoding 15q11-13 sno-lncRNAs ispecificallyly deleted in human PWS.
To this end, we generated a conditional RTCB knockout mouse model, Rtcbfl/fl Cd23-Cre, in which RTCB is specifically deleted in mature B cells.
In our sec8 null mutants, in which the sec8 gene is specifically deleted, Sec8 immunoreactivity at the NMJ is eliminated but immunoblots reveal substantial maternal contribution in the rest of the animal.
The myelination of P0-Cre Nf2flox mice, where merlin is specifically deleted in Schwann cells only, instead appeared decreased (Fig. 2C), resulting in a g-ratio gain because the axon diameter was also statistically reduced (not shown).
To evaluate the role of Ihh in OA development, Ihh was specifically deleted in murine cartilage using an Ihh conditional deletion construct (Col2a1-CreER T2 ; Ihhfl/fl).
In another mouse model, Fto was specifically deleted in the neural system.
To address this question, we constructed a strain of mice in which Geminin was specifically deleted from neural stem cells.
To address this question, we created a strain of Nestin-Cre/Gmnnfl/fl mice in which the Geminin gene was specifically deleted from NSCs.
The lack of these specific phenotypes in the Dmpk−/− and Six5−/− mice suggests that these genes do not play a role in motivation when they are specifically deleted but their dysfunction, as caused by the DM1 trinucleotide repeat expansion, may still participate in generating cognitive effects in patients.
