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A non-steady pattern of rupture bands is shown to develop from the discharge outlet towards the traction-free boundary of the material in the initial stage of flow.
A row of voids growing by stress driven boundary diffusion is shown to develop a tensile stress maximum which aids void nucleation, giving rise to dimpled grain boundary fracture.
This effect is shown to develop through JAK2/STAT3/p38 MAPK pathways (Nickola et al., 2000; Wold et al., 2002; Sharma et al., 2009; Lopaschuk et al., 2010), and interestingly, RhoA/ROCK-mediated cardiac hypertrophy is p38 MAPK-dependent (Zeidan et al., 2006; Zeidan et al., 2008), intimating p38 MAPK as a critical pathway involved in dysregulated metabolic and hypertrophic mechanisms.
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While large doses of the chemical, are known to cause nerve damage in people, acrylamide is deemed "a probable" human carcinogen by the Environmental Protection Agency because only rodents have been shown to develop tumors from exposure to it.
Large residual microstrains are shown to develop.
In mice, parthenogenetic stem cells were shown to develop abnormally.
Inclined strain localization bands are shown to develop at ∼800 μm from the notch prior to the onset of damage.
In addition, up to 41% of EVAR patients have been shown to develop post-procedural complications, with 20% subsequently requiring fluoroscopically based radiological re-intervention [1].
In addition, niosomes have been shown to develop absorption of some drugs across cell membranes, and localize in targeted organs and tissues to elude the reticuloendothelial system [110].
"Animal-Animal" chimeric embryos have been shown to develop into a target organ by using blastocyst complementation (Kobayashi et al. 2010; Matsunari et al. 2013).
Similarly, children with IL-12 receptor β1 (IL-12Rβ1) deficiency have been shown to develop the severe form of TB, frequently [13].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com