The independent risk factors after multivariate analysis were sensitisations to flour and storage mites (table 3).
One possible explanation is that sensitisation occurred prior to the provision of the intervention - equally in both groups.
Even the maximum amount of £9,190 saved per additional sensitisation is much lower than the figure of £15,903 - £17,668 judged acceptable for avoiding a sensitisation by NICE [ 42].
For the purposes of this clinical research, the term pain sensitisation will be utilised, however, the lack of a widely accepted definition and criteria for identifying pain sensitisation is acknowledged as a limitation.
Sensitisation is detectable by reaction to a skin-prick test.
In the appeal court judgment, Lord Sales said: "On the medical evidence, platinum sensitisation is not harmful in itself in any relevant sense.
The mechanism of the drug sensitisation is not clear.
The skin sensitisation is a well defined endpoint of specific utility within the REACH framework.
Chronic widespread pain/FM is characterised by sensitisation of central pain pathways.
Stress sensitisation is thought to be an underlying mechanism and may be reflected in an altered autonomic stress response.
