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Data accuracy is routinely validated through provincial and central Canadian agencies.
The database is routinely validated by comparison with hospital archives before being available for statistical or research purposes.
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Many large scale STEM experimental techniques are routinely validated using imaging or diffraction simulations.
Malawi has established a standard, national monitoring system for ART used by all public and private sector facilities, the data are routinely validated during quarterly supervision through cross-checking of master cards and ART registers, ensuring high data quality.
Where possible, the biosensors are routinely validated by testing them in the p53- background.
Inherited variants will not be routinely validated due to the extremely high positive predictive value of such calls.
All methods were routinely validated with control serum samples and additional standard set points (two analytic standards, one low and one high concentration were used as set points).
The specificity of antibodies used for immunoprecipitation was routinely validated by running negative controls using non-immune IgG using the same conditions as in formal experiments.
These models include the current gold standard approaches using type II collagen-induced arthritis in both the mouse and rat, and have been used extensively for benchmarking novel therapies while being routinely validated against current standards of care (methotrexate and prednisolone).
Identifications with one or two sequence-unique peptides were routinely validated using the MaxQuant Expert System software [ 67] considering the assignment of major peaks, occurrence of uninterrupted y- or b-ion series of at least four consecutive amino acids, preferred cleavages N-terminal to proline bonds, the possible presence of a2/b2 ion pairs and immonium ions, mass accuracy and score.
Furthermore, the data lacked clinical detail on radiation fields, doses, and duration of treatment, and we had no information on chemotherapy or disease stage; radiotherapy details (yes/no) from the Cancer Registry may be inaccurate, because they are not routinely validated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com