Although doctors assume that the treatments are more or less equivalent to prostate surgery, that has not been rigorously demonstrated, nor has it been shown that these treatments prevent prostate cancer deaths.
In its ideal form metaphysics would be presented in a manner analogous to Euclid's Elements, where propositions are rigorously demonstrated on the basis of definitions and axioms.
Despite the accumulating knowledge on the role of cytoplasmic PNGase in the ERAD and the conservation of its structural features in species from yeast to mammals [17], [18], [19], [20], [21]), the biological significance of this protein has not yet been rigorously demonstrated in any system.
9 10 While the value of such measures has been rigorously demonstrated, they have limitations.
It is debatable if dependence on the 3'BE and on translational repression has been rigorously demonstrated.
Both the sensitization and the elicitation processes are probably thresholded although this has not been rigorously demonstrated for sensitization.
Although it has not been rigorously demonstrated, it is believed that the two DNA helices at the crossover become the G- and T-segments.
Authors also increasingly highlight that quality improvement interventions have seldom been subject to critical investigation and their effectiveness has not been rigorously demonstrated [ 26- 29].
However, its equivalency or superiority to TEC has never been rigorously demonstrated, thus TC therapy is not currently an established regimen for endometrial carcinoma.
In conclusion, while a contribution of C1orf124 to the regulation of TLS appears likely, neither its mechanism nor its net effect has been rigorously demonstrated.
While the safety and efficacy of the FSPT used in this population have been rigorously demonstrated [ 14], its widespread promotion is still subject to further evaluation especially regarding how to handle interruptions due to inclement weather conditions.
