Sentence examples for is required for functioning from inspiring English sources

Taken together, these data suggest that like mammalian importin β, Ketel mediates the nuclear localization of PER, and consequently, is required for functioning of the core circadian clock.

First, the onset of pathology in LE patients suggests that LGI1 is required for functioning of fully developed synapses, in addition to its role in synaptic maturation (Owuor et al., 2009).

While some increase in segregation efficiency of plasmids is derived from having either one of these elements, high segregation efficiencies were only achieved when both the PCEN repeat and core regions are present, indicating that the entire A/T-rich sequence (i.e., both the core and the repetitive regions) is required for functioning of a centromere.

In Drosophila, functional activity of Ago-1 requires cytokinesis regulator sticky/citron kinase protein for silencing at transcriptional level [ 98] whereas in S. pombe, Ago-1 interacts with 14-3-3 14-3-3 14-3-3this interaction is required for functioning of Argonaute proteinsin cell cycle and/or gene-silencing pathisys [ 99, 100].

This repeat is preceded by a conserved A/T rich sequence that is required for function.

ATP hydrolysis by Rvb1/2 is required for function; however, the mechanism that drives substrate remodeling is unknown.

Par-6 PDZ regulation is required for function as mutational disruption of Cdc42-Par-6 PDZ coupling leads to inactivation of Par-6 in polarized MDCK epithelial cells.

Structural modeling suggests that the MPER forms an α-helical coiled coil that is required for function and immunogenicity.

If the C-terminus of a protein is required for function then this will not be an appropriate method.

Our studies clearly indicate that Ppt1 protein is expressed ubiquitously at a very low level such that only a minute amount is required for function.

Although the cytoplasmic domain of the receptor alpha chain is required for function [13], [14], it does not appear to be associated with any signaling kinases [15] [17], [34].