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REQUIRED RULE: GKFC in peptide is required for cell adhesion [ 31].
The coordinated and dynamic regulation of focal adhesion is required for cell migration.
Studies in numerous adherent cell systems have indicated that engagement of integrins is required for cell survival and proliferation.
Thus, kermit2 is required for cell migration on, but not adhesion to, FN.
Therefore, Wnt signaling is required for cell proliferation in zebrafish swimbladder.
Sit4 is required for cell cycle transition from late G1 phase to S phase [2], [20].
This process is required for cell cycle progression to occur (reviewed in [33]).
Sustained ERK activation is required for cell cycle progression through G1 phase [18].
Thus we determined whether ACTN4 is required for cell migration by performing an in vitro 'wound healing' assay.
Degradation of peptidoglycan is critical, since cell wall plasticity is required for cell shape and cellular division.
Our time-lapse recordings clearly demonstrated that active protrusive activity is required for cell movements during zebrafish gastrulation.
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