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Hsp90 is reported to function in protein degradation, in addition to its role in protein folding, via its association with CHIP, an E3 ubiquitin ligase [16].
Although MCPH1 is reported to function in multiple cellular processes, its regulation is not well understood.
23 In contrast to Notch1 and Notch3, Notch2 is reported to function in a tumor-suppressive manner in NSCLC.
Interestingly, SIRT2 is reported to function as an H3K18 deacetylase in the context of Listeria monocytogenes infection.
Undercarboxylated osteocalcin (ucOC) is reported to function as an endocrine hormone, affecting glucose metabolism in mice (1, 2).
ERK5 is reported to function as an IKKα kinase, promoting I κB degradation and consequently NF- κB release from I κB.
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Although AtMYB3 and AtMYB7 have not been functionally characterized, AtMYB4 has been reported to function as a repressor of the lignin biosynthesis pathway [ 25].
Oral supplementation of clay has been reported to function as buffer in dairy cows.
OsWRKY71 has also recently been reported to function as a transcriptional repressor (Chujo et al. 2008).
Squid ink was reported to function as antioxidant in hyperlipidemia rats and broil chicken (Lei et al. 2007; Liu et al. 2011).
Many of these have never been reported to function in these cells types.
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