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Although the conventional SSD approach is adopted in the German RAA 2008 design guidelines as well, in situations of SSD shortage, it is recommended to modify the road alignment or decrease the speed limit.
If the treatment goal is not met, it is recommended to modify therapy.
(Delphi-result: vote 19/19 = agreement, round 3) "If at the end of the induction phase an improvement of PASI of ≥50% (∆PASI ≥ 50%) as compared to disease severity at the time of treatment initiation has not been achieved, it is recommended to modify the treatment regimen".
(Delphi-result: vote 17/19 = agreement, round 4) "If during maintenance therapy an improvement of PASI of ≥50% (∆PASI ≥ 50%) as compared to disease severity at the time of treatment initiation has not been achieved, it is recommended to modify the treatment regimen".
(Delphi-result: vote 17/19 = agreement, round 4) "If during maintenance therapy an improvement of PASI of ≥50% but of less than 75% (∆PASI ≥ 50%<75%%) as compared to disease severity at the time of treatment initiation can be maintained, but DLQI ≤ 5 has not been achieved, it is recommended to modify the treatment regimen".
(Delphi-result: vote 19/19 = agreement, round 3) "If at the end of the induction phase an improvement of PASI of ≥50% but <75% (∆PASI ≥ 50%<755%) as compared to disease severity at the time of treatment initiation has been achieved, but DLQI ≤ 5 has not been achieved, it is recommended to modify the treatment regimen".
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For example individuals who are seemingly healthy but are found to have a high risk of developing cardiovascular disease could be recommended to modify their lifestyle and behaviour (e.g. smoking, exercise, eating habits) to reduce their future risk.
For participants whose BP was subsequently judged by their physician to require additional medication, it was recommended to modify treatment in accordance with the IDF Type 2 Diabetes European Policy Group guidelines [ 31].
It is recommended to use modified Pesticide DRASTIC for weathered rock regions with irrigation practises and shallow aquifers (<20 m bgl).
If the therapeutic effect is a reduction in PASI of at least 50% but less than 75%, it is recommended to decide whether to modify the therapeutic regimen according to DLQI.
In the ITU-T test plan draft [18], it is recommended to take the modified RMSE as primary metric and Pearson correlation as informative.
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