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CtsB is recently implicated in activation of NLRP3-inflammasomes by crystalline structures [77], [78] and in caspase-1 cleavage [76].
As ER stress is recently implicated in the pathogenesis of heart diseases such as ischemic heart disease and heart failure [12], [13], we analyzed the expression of ER stress markers such as GRP78 and C/EBP homologous protein transcription factor (CHOP) in this model, and found that these ER stress markers were induced at the phase of transition from hypertrophy to heart failure (Fig. 2C).
Besides caspase-mediated apoptosis, autophagy is recently implicated to be important in cell survival and death.
Iron metabolism alteration in the central nervous system is recently implicated as a risk factor for several neurodegenerative disorders.
96 Another prominent member of the lncRNAs that is recently implicated in cancer is SChLAP1, which was identified as an overexpressed gene in prostate tumor samples.
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He was recently implicated by opposition leaders in a military deal involving the sale of 10,000 Russian assault rifles by the Peruvian military to a rebel group in Colombia.
TERT promoter mutations have been recently implicated in urothelial carcinogenesis.
The meninges have also been recently implicated in pain processing even at spinal levels [22].
Non-coding RNAs (ncRNAs) have been recently implicated in several molecular mechanisms in eukaryotes.
Another lysophospholipid mediator lysophosphatidic acid has also been recently implicated in fibrosis.
Mitochondrial dynamics, the processes including mitochondrial fusion, fission, biogenesis and mitophagy, have been recently implicated in cerebral ischemia injury.
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