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Antimicrobial immunity involves adaptive immunity, however, which also is readily activated by TLRs [ 45, 46].
As a result, the receptor is largely insensitive to 17β-estradiol, but is readily activated by 4OHT [ 15].
IAV infection up-regulated both proMMP-2 and proMMP-9 in the myocardium and cardiomyoblasts, with only marked proMMP-9 activation, but not proMMP-2, probably because proMMP-9, but not proMMP-2, is readily activated by induced trypsins.
Moreover, although plg displays widespread cell-surface binding to a range of putative receptors, it is the uPA-co-localised fraction of plg that is readily activated to pln [ 28].
Compound 2 is readily activated by heating under vacuum to remove the DMF and water guests to afford a three-dimensional porous material with a surface area of 4116 m g−1 and pore volume of 1.55 cm g−1.
The failure of VIP to augment macrophage IL-10 production, unlike the murine system, is likely to result from the lack of activation/phosphorylation of CREB, a transcription factor that is readily activated in the murine system by VIP [ 10].
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Consistently, the promoter regions A2, A3 and C, lacking AP-1 binding sites (Supplemental Fig. S1), were readily activated by Nter-142Q (Fig. 3), likely by the activity of transcriptional factors other than AP-1.
Compared with A549 cells, BDNF had no effects on Pyk2 and ERK activations or the invasion of HBE cells, which suggested that in TrkB-positive A549 cells, up-regulated TrkB was readily activated upon BDNF, and signaling pathways initiated by TrkB led to an immediate activation of Pyk2 and Pyk2-mediated functions.
We find that slip systems with large interplanar distances are readily activated, which agrees well with experimental observations.
We utilized this characteristic to prepare Src-like tyrosine kinases that can be readily activated with the rationally designed chemical inducer of dimerization FK1012.
Most schools also request parents' e-mail addresses at the start of the year, which some use to create an e-mail database that can be readily activated to send urgent or routine notices.
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