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In case anyone thinks that all this is rather drastic they should ponder the fact that the big investment banks and insurance houses are already bidding to take over and merge company schemes.
Similar observations can be made from Figure14 depicting the delay CDF; we note that though the delays for R-UEs are lower as compared to Figure12, the degradation in the performance of M-UEs is rather drastic.
This approach is rather drastic, but it is efficient to avoid out-paralogs in the resulting file.
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Therefore, since the light stress conditions used in this work to induce photooxidative damage were rather drastic (1500 μmol photons m-2 s-1 at 6°C), a leakage of O2 from the chloroplast to the cytosol cannot be excluded and therefore an action of vitamin B6 within the cytosol is also possible.
However, protein structure is rather robust, and in many cases mutations do not have a drastic effect on protein structure.
Thus, it appears that an outright knock-out of G6PD is too drastic, whereas in the available mutant mice G6PD deficiency is rather mild.
This is a rather drastic measure though and should only be considered as a last resort, such as where a parent with dementia is clearly incapable of dealing with financial issues.
Deleting your Facebook account permanently is a rather drastic action.
The growth of dendrites appeared to be rather constant without drastic changes in overall arrangement.
The first disease mutant desmin to be analyzed at the in vitro level for its assembly properties was the rather drastic p.Arg173_Glu179del desmin "rod" mutation, which misses seven amino acids in a row in coil 1B.
Still, it's a rather drastic change -- what do you think?
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com