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Reliable evaluation of risk of building damage due to the mining impact is problematic owing to the magnitude, diversity and uncertainty of factors that may affect the surface, as well as the subjective character of methods of assessing resistance of the objects.
Local gene delivery into bone is problematic owing to the limited accessibility of the interior of bone, and its trials have remained preclinical for a long time [1], [13].
Differentiating cerebral malaria (CM) from other causes of serious illness in African children is problematic, owing to the non-specific nature of the clinical presentation and the high prevalence of incidental parasitaemia.
81, 108 However, meta-analysis here is problematic owing to the heterogeneous nature of study populations and interventions used.
Comparing studies is problematic owing to the different tools used to assess self-reflection and academic performance in each institution.
Elucidation of the causes of NTDs is problematic owing to their complex, multifactorial etiology and largely sporadic nature (Bassuk and Kibar, 2009; Greene et al., 2009).
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The analysis of coverage from MDA drug registers has been shown to be problematic owing to overreporting [ 30].
Comparisons across studies were problematic owing to heterogeneity of data and highly variable methodology, presentation techniques, and missing data.
The representative dose distribution of a RapidArc plan is shown in Figure 2. Radiation therapy for head and neck cancer can be problematic owing to the anatomy of this region, forasmuch as these tumors are generally adjacent to the critical organs where limiting dose irradiation is necessary.
The relationships among Arabian toad species have long been problematic, owing in part to the generalized morphology of these species and of lineages in surrounding regions [ 33, 45].
In the general, the popular vote is somewhat problematic owing to the bifurcation between battleground states, where turnout is high, and spectator states, where it's low, and differences in voter eligibility, such as whether or not ex-offenders are deprived of the franchise.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com