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Ammonia, as a gas (NH3) and ion (NH4 +), freely crosses the blood brain barrier and is primarily removed by glutamine synthetase, an enzyme solely found in astrocytes within the brain [6].
Although endogenous and environmentally induced DNA damage is primarily removed by DNA repair mechanisms (including nucleotide excision repair, base excision repair, mismatch repair, and various forms of strand break repair), some damage may remain, which can block progression of the normal DNA replication machinery.
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The experimental results showed that the COD and color were primarily removed by direct ozone oxidation and activated carbon adsorption.
The coulombic efficiency suggested that the nitrate was primarily removed by bioelectrochemcial denitrification in the inner cathode, especially at the low nitrogen loading rates.
Static geoidal height which depends on location (~101 m) was primarily removed using the EGM 2008 model (Pavlis et al. 2012).
Before using PPI dendrimers in vivo, their interactions with macrophages must be fully understood because they are primarily removed from circulation by the macrophages of the mononuclear phagocyte system.
Before using catanionic vesicles in vivo, their interactions with macrophages must be fully understood because they are primarily removed from circulation by the macrophages of the mononuclear phagocyte system.
Pharmaceuticals in the aquatic environment are primarily removed by three degradation pathways: sorption, biodegradation and photolysis.
Tobacco-induced DNA adducts are primarily removed by nucleotide excision repair (NER) pathway.
Top1-DNA adducts are stabilized by camptothecin (CPT) and are primarily removed by the phosphodiesterase Tdp1 (Pouliot et al., 1999).
However, delivery of chemotherapy in patients with concurrent end-stage renal disease (ESRD) can be hindered as drugs like cisplatinum are primarily removed by haemofiltration.
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