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The side chain of this ligand is predicted to extend along the enzyme active site gorge from the anionic subsite, at the bottom, to the peripheral anionic site, at the top.
Mutation XV is predicted to extend the encoded peptide product by 6 aa.
In wild type Cav1.4, the hydrophobic side chain of Leu860 is predicted to extend into the hydrophobic core of the membrane (Fig. 1c).
Amino acid A659 (d N /d S >1 in all mammals) is located in the transmembrane region and is predicted to extend this domain.
Similar(56)
Hurricane-force winds were expected to extend up to 35 miles from Harvey's center, and tropical-storm-force winds were predicted to extend as far 140 miles, putting cities including Houston, Galveston and Corpus Christi at high risk.
Obviously, the effects were predicted to extend from the JAK-STAT3 pathway to multiple networks in the cancer cells.
Additionally, the α-helices in the Y21 and CH-CD structures are predicted to extend almost completely through to the C-terminus.
For example, T. barberi was predicted to extend broadly across central and southern Mexico, and populations were predicted in several regions (e.g., northern and eastern Michoacán and southern Hidalgo) for which previous occurrence data were not available.
The signatures of balancing selection are predicted to extend over short genomic distances [ 54, 55]; nonetheless we wished to verify that the evolution of Ex2 is not influenced by the presence of a linked balanced polymorphism located elsewhere.
51 The A53T mutation is predicted to disrupt the α helix and extend the β sheet structures, thought to be involved in protein misfolding and self-aggregation.
The amino acid sequence is predicted to form a longer α-helix extending into the outer membrane.
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CEO of Professional Science Editing for Scientists @ prosciediting.com