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The study is powered to detect a difference in HbA1c of 0.3 units between the groups.

The study is powered to detect a 20% decrease in triglycerides with the lifestyle intervention and an additional 20% improvement with the addition of niacin and/or fenofibrate.

Like any Phase 1 study, it is powered to detect only frequent events or large differences.

The study is powered to detect relatively large effect sizes.

Finally, this study is powered to detect a medium effect size.

The trial is an exploratory study but is powered to detect differences in urge to smoke.

The study is powered to detect a 50% reduction at a 0.8 power.

This implementation study is powered to demonstrate a medium or higher effect of TTA.

However, the study is powered to detect main effects of half this size.

The trial is powered to allow the THR and TKR groups to be analysed separately.

This study is powered to establish clinical equivalence using the PCS scale from the SF-36.

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