Our final experiment (Experiment 5) demonstrated that the fluoxetine-induced decrease in the enhanced cholinergic neurotransmission is possibly mediated through M1 muscarinic receptors.
In conclusion, our findings indicated that exogenous rh-NTN-1 treatment attenuated neuroinflammation and neurological impairments through inhibiting microglia activation after SAH in rats, which is possibly mediated by UNC5B/PPARγ/NFκB signaling pathway.
These results suggest that a step increase in tensile stress and strain in experimental vein grafts induces rapid cell death, which is possibly mediated by cell death signaling mechanisms.
The heating duration effect is possibly mediated through deleterious effects on tumor oxygenation.
In gastropods the perception of environmental chemical stimuli originating, for example, from food or other organisms is possibly mediated by sensory organs such as the osphradium.
Studies also suggest that lifespan extension by dietary restriction in several species including mice is possibly mediated by reduction of mTOR/S6K1 signalling [6].
Recently it has been shown that ABCG2 plays a role in enhancing the survival of haematopoetic stem cells in hypoxia, which is possibly mediated through transportation of heme and porphyrins [15].
This response is possibly mediated by the TH protein up-regulation and also by an important post-synaptic event defined as D2 dopaminergic supersensitivity [12], [13], [14], which is unleashed mainly by reduction of DA in the synaptic cleft.
However, we did observe the association between MARγ and MARHS4/MARHS2 as shown in 3C assay (Fig. 2), suggesting that the association is possibly mediated by other trans-acting factor(s).
This effect is possibly mediated through binding sites for NF-κB/Rel proteins in a regulatory module of the scute gene required for maintenance of scute expression in precursors as well as repression in cells surrounding precursors.
This solubility is possibly mediated by negatively charged regions at the coiled-coil, since the mutants ΔN141 and ΔN197, which lack parts of these regions, are TX-100-insoluble.
