Elucidation of molecular assembly mechanism of protein-based suprastructure formation is pivotal to develop biomaterials.
In the clinical setting, it is pivotal to develop strategies with adequate positive and negative predictive power to discriminate between responders and non-responders, since it is estimated that only half of the ICU patients is 'fluid responsive' [7].
Finally, more basic research on the underlying mechanisms with regard to vessel co-option is pivotal to develop potential new treatment strategies.
Identification of synergistic/complementary properties of biostimulants can be pivotal to develop specific formulations targeted to enhance plant response to abiotic stress.
However, it is pivotal to dissociate the propensity to develop habits, which in itself is not an aberrant process, from the inability to regain control over maladaptive habits that have become inflexible, such as those that are seen in addicted individuals who compulsively seek and take drugs.
A better understanding of the meaning and rationale for innovation, as perceived by the rapidly-growing youth population in developing countries, is pivotal to the design of practical and sustainable technology innovations and entrepreneurial ecosystems.
In support to a pro-metastatic role of Nupr1, Ree et al (1999) have reported that Nupr1 overexpression is pivotal to the breast cancer cells that develop metastasis in the central nervous system.
There is a growing body of scientific evidence that early childhood care is pivotal to how a child grows and develops from birth to up to the eighth year -- and can greatly influence a child's continued learning and psycho-social development in the later years.
In this respect, transcriptome profiling of developing Gb and Gh fibers is pivotal to discovering the specific genetic program that drives the development of fiber in these genotypes.
Although normal β-cell function is pivotal to the maintenance of NGT, β-cell failure develops long before hyperglycemia becomes evident.
