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One might worry that this supposition is overly strong.
We think it is overly strong to state that these authors arrived at a wrong conclusion as this manuscript's major conclusion, in our view, was that these two enzymes interact.
There is no mention of alternative models in the Discussion and the title is overly strong in its assertion given the weak, and by the authors' own admission, indirect, connection between physical stress and STM expression.
There is no mention of alternative models in the Discussion and the title is overly strong in its assertion given the weak, and by the authors' own admission, indirect, connection between physical stress and STM expression.To clarify again: the fact that STM slows down growth and induce folding is not an alternative hypothesis, it is a fact.
Similar(56)
If you're overly strong in any of those areas, odd things can happen".
Our initial manuscript was overly strong in its statement of the association between the stabilizing/destabilizing mutations and the adaptive mutations.
This 17N mutation is well characterized in Ras and Rho small GTPases as conferring potent dominant-negative activity, and the main caveat with this reagent is that it could be overly strong by sequestering GEFs required for activation of other Rho family members in addition to CDC-42.
Rather, the ride highlights bumps in the road but the suspension still feels loose; the steering is overly light and lacking a strong on-center feel.
In a blog post Monday, web hosting company DreamHost detailed that it has been working with the federal government for months over the information request, but says the order is overly broad and represents a "strong example of investigator overreach and a clear abuse of government authority".
Although this framework is overly bureaucratic in focus it has strong face validity (estimate of the degree to which a measure is clearly and unambiguously tapping the construct it purports to assess) in recognising that a HIA may have more than one type of effectiveness, but also that the impact may not be linear and may not be directly attributable to the HIA.
Bonferroni correction is overly conservative when hypothesis tests are correlated, and there is strong a priori evidence supporting the hypothesis tests, as is the case here.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com