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Recently a new functional constitutive relation was derived by Saimoto and Van Houtte based on Taylor slip analysis that is optimally fitted to replicate the measured data.
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A three-pool (active, slow, and passive) C-cycling model was optimally fitted with 376 published laboratory incubation data from soils acquired from 73 sites with mean annual temperature ranging from − 15 to 26 °C.
For example, problem Histamine H _2) receptor (HRH2) is a worst generalized model constructed by unscaled importance based feature selection, but was optimally fitted by the scaled importance based set of features.
Similarly, the side-chain of W6 was optimally fitted with the side-chain of M10 to create a hydrophobic motif at the core of the structure (see Figure 10B).
For example, the side-chains of A1 and F3 were optimally fitted with the side-chains of V11 and W13 to create a hydrophobic motif at the edges of the assembly (see below and the model in Figure 10B).
The technique involved custom femoral stems, whereby the prosthesis was optimally fitted to the femoral cavity and the extramedullary joint anatomy of each patient was reconstructed according to CT data in order to help to reduce prosthetic impingement and dislocation, and to improve joint mechanics.
Although the cryo-ET density could be optimally fitted only by extended forms similar to the X-ray YscD conformation, MD snapshots of individual monomers in more compact forms allowed the construction, without incurring in steric clashes, of YscD 24-mer ring structures representative of possible states of intermediate compression compared to the fully extended ring model.
All three resulting clade-specific diversification models were optimally fit as Yule models (AIC = 339.3032).
A consequence of these tradeoffs is that they prevent 'Darwinian demons': single super-genotypes that are optimally fit across a spectrum of environments [ 2].
The commonly invoked cost-benefit paradigm, central to most of functional biology, explains why one phenotype cannot be optimally fit in all environments; yet it is rarely tested.
The corresponding structure in the spectral residuals gives an indication of the spectral identity of the component(s) that is (are) not optimally fit.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com