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Furthermore, although PDE5A regulates nitric-oxide-generated cGMP4,5, nitric oxide signalling is often depressed by heart disease6.
However, nitric oxide signalling is often depressed in cardiovascular disease, potentially explaining the disappointing results of PDE5A inhibition in clinical trials.
He sorely misses the family he left behind in North Korea, is often depressed and wants nothing more than to go home.
The cap center is often depressed.
She is often depressed and scared to even tell anyone what is going on in her world.
Because IQ is often depressed in SCTs, IQ-matched comparison groups can be informative in establishing whether any problems are compatible with generally lower intellectual functioning or are a more specific correlate of the SCT.
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Ruth Marcus: Trump is often depressing.
Fiction feeds on conflict, and conflict is often depressing.
TRAVELING in England today, some writers tell us, is often depressing.
Self-absorption is one of many reasons for skyrocketing rates of depression in the United States, as human beings are often depressed to the extent that they are exclusively preoccupied with their own needs.
In their solitary hours, they are often depressed and terribly homesick.
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