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QOL PCD is now being validated in Europe, USA and Canada; the psychometric reliability and validity will be reported when these studies are complete.
An amphibian assay (XEMA) based on the T3-dependent metamorphosis of tadpoles using the model X. laevis has been developed and is now being validated (Degitz et al. 2005; Opitz et al. 2006).
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Within the past 5 years, genetically modified (GM) algae have entered strain development pipelines and are now being validated for commercial-scale cultivation.
Turns out, there are some amazing benefits that are now being validated by actual research on adult coloring.
Two potential biomarkers, apolipoprotein A-1 and chemokine (C-C motif) ligand 17, were identified, and are now being validated in the current pivotal phase 3 trial.
The RIFLE (Risk, Injury, Failure, Loss, and End-stage kidney disease) criteria [ 25] proposed by the ADQI group were developed by an interdisciplinary, international consensus process and are now being validated by different groups worldwide [ 36, 37].
The study has led to a realization of the importance of obtaining a simple method of summating damping, and further work is now being done to validate such a method.
A further large prospective, randomized, placebo-controlled study (STELLA) is now being conducted to validate this study results (http://www.clinicaltrial.gov/ct2/show/ NCT01444885?term=cilostangina&ranksospastic+ angina&rank = 1).
For these reasons - diagnostic uncertainty, the need to distinguish, early on, those at greatest risk, and (as discussed below) the need to monitor treatment effects - much effort is now being devoted to developing and validating so-called biomarkers.
A multicenter, prospective study is now being performed on a second cohort to validate accuracy, adequacy and reliability of this score.
This latitude of scientific exploration, as well as preliminary positive results has steered the field, according to Arlen, from "'this is really voodoo' to now being validated and approved".
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