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This is not that problematic as long as one is only interested in characterizing the methylation status of extended genomic regions such as CpG islands, promoters, non-coding RNAs, or gene bodies.
Actually, suburban competition is not that problematic.
As long as black holes were thought to persist forever this information loss is not that problematic, as the information can be thought of as existing inside the black hole, inaccessible from the outside.
However, it is also possible that the released H2O2 is not that problematic for cellular function.
It can be argued that the lack of a more sophisticated case-mix measure for dental care is not that problematic, compared for instance with specialized hospital care, as the variation of resource use and the complexity of care across patient cases is not significant.
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"The figures are not that problematic at this time," Mr. Smet said, "but we see that the numbers are mounting, so we do need to monitor it".
The point is not that adopting new technology is always problematic, but that the repro-libertarian framework for evaluating it is naïve and misleading (Sherwin 1992).
It's not that any of these posts are problematic.
It may be argued that the absence of general practice elements from pandemic plans is not problematic, that it is outside the responsibility of public health departments that do not have a governance role for general practice.
The latter is not so problematic, in that "being a surrounding" can be an extrinsic property of the event in question.
That is not merely problematic; it is wholly dangerous.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com