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Thus, it is not straightforward to predict where and in which composition (Ba,Sr SO4 solid-solutions will form in a geothermal water circuit.
Thus for any given highly variable target it is not straightforward to predict, by simple inspection of the sequence or of alignments, either whether such a probe design approach will work at all, nor what the optimal probe length is.
Because many of these genes do not encode metabolic enzymes, it is not straightforward to predict the ensuing change in expression cost from a metabolic model.
In addition, since nAChRs are found on both inhibitory and excitatory neurons in different PFC layers, it is not straightforward to predict how action potential firing of PFC output neurons is altered by nAChR stimulation.
However, it is not straightforward to predict whether this "hypoxic effect" would be also observed in other expression systems like S. cerevisiae, as yeasts behave in a different way with regard to their capacity to secrete, to process and to modify proteins in particular cases.
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Thus, this entry was not straightforward to predict the biological state.
Due to the microanatomy of this organ with exocrine and endocrine components intimately connected and its embryonic origin from two separate evaginations of the primitive gut epithelium, potential stem cell markers are not straightforward to predict from knowledge about pancreatic development.
Unfortunately it is not straightforward to translate an expected protective efficacy at day 35 post 3 and 9 month dose predicted by the model at different frequencies of mutations to an equivalent 12 month protective efficacy.
Even economic benefit is not straightforward to assess.
However, it is not straightforward to interpret.
Structure-property relationships, central to many of today's drug discovery strategies, are not straightforward to deal with when trying to predict drug efficacy, that is, the combined outcome of target affinity, pharmacodynamic behavior, pharmacokinetic properties, and metabolic fate.
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