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Our work highlights the fact that kinases can access conformational space that is not necessarily utilized for their native catalytic regulation, and that such conformations can explain and be exploited for inhibitor specificity.
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The concept of biome is not necessarily compatible with the actual land use and the way forests are managed and utilized.
However, the main advantage of utilizing a prior model for the fraction defective is not necessarily reduced sample size but improved assessment of the true sampling risks.
This is not necessarily deplorable.
He is not necessarily wrong.
That is not necessarily true.
This is not necessarily unwise.
Loudness is not necessarily persuasive.
It is not necessarily either.
It is not necessarily innocent.
That is not necessarily so.
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