Sentence examples for is not mediating from inspiring English sources

As shown in Fig. 1C, diazoxide did not inhibit glucose-mediated activation of PDE3B, indicating that glucose is not mediating its effect via endogenously produced insulin.

Based on this new data we can conclude that blocking PI3K signaling is not mediating differentiation via selective apoptosis.

Acetylation of the lysine residue (K16KAc, 7) or substitution with arginine (K16R, 8) resulted in a conversion to the deacetylated product similar to that of the parent peptide, suggesting that K16 is not mediating specific or electrostatic interactions with HDAC8.

We therefore used siRNAs to suppress the PI3K-p110α PI3K-p110αsubunit and found no evidencatalyticome editing outcome indicating that PI3K-p110α subunitsion is not mediandng the efounds of no7441 or KU-0060648 (Fig.  1c, d).

However, it is important to note that even though PGC1α mRNA increased with the addition of the anaplerotic agents, and this is a good indicator of PGC1α activity, we did not see an increase in PGC1α protein compared with the NaCl controls, raising the possibility that PGC1α is not mediating the metabolic recovery.

However, Hairy is not mediating only one average type of transformation; removal of methyl groups from H3K4me1 and H3K4me3 is catalyzed by distinct classes of enzymes; Hairy is likely to interact with both, allowing for removal of H3K4me1 marks on distal sites and H3K4me3 at TSS.

The effect of progesterone is not mediated by the nucleus but is a direct effect on the cytoplasm.

This effect is not mediated by any intervening cause.

In neutral solution, reaction of the Fe CN 3−2−6 couple is not mediated at the coated electrode.

This further suggests that the effect of rizatriptan on motion sickness is not mediated via changes in "velocity storage".

The first is a better capacity to control parasitaemia and is not mediated by haemopoietic cells, T lymphocytes or antibodies.