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An antimetabolite is similar in structure to a metabolite, or enzymatic substrate, which is normally recognized and acted upon by an enzyme to form a substance required by the cell.
Mitochondrial fission is normally recognized as an early event during apoptosis.
Thus, we propose a novel regulatory model in which an unmethylated (or partially methylated) PPARG core promoter region is normally recognized by unknown transcriptional activators, among which only the zinc-finger protein ZAC has been identified so far in CRC cells [23].
DNA damage is normally recognized and repaired by the intrinsic DNA damage response machinery.
As ENU-induced DNA damage is normally recognized by the mismatch repair (MMR) system, we hypothesized that the effectiveness of the target-selected mutagenesis approach could be improved by using a MMR-deficient genetic background.
For example, a person who is chattering on about themselves selfishly or bragging is normally recognized as arrogant or self centered.
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Fellows are normally recognized for a substantial body of scientific work, which makes election before the age of 40 years unlikely.
Following apoptosis, dying germ cells are normally recognized, engulfed and gradually degraded by the surrounding somatic sheath cells [27] (Fig. 1G, G', H).
Hyperalert delirium symptoms are normally recognized more by intake physicians or bedside nurses, while the less obvious symptoms of hypoalert delirium may often escape the clinician's attention.
From these results, we conclude that Azot expression is activated in several contexts where suboptimal and viable cells are normally recognized and eliminated.
We used minigenes to demonstrate that this mutation is the direct cause of MTRR pseudoexon inclusion, and that the pseudoexon is normally not recognized due to a suboptimal 5′ splice site.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com