Regarding the assessment of the potential haemodynamic significance of a given coronary artery stenosis though, the use of proper stress testing is necessary in combination with myocardial perfusion imaging, as coronary luminal changes may compensate for a wide range of coronary luminal changes and therefore mask the presence of even high-grade lesions [82, 84].
To overcome the radioresistance of apoptosis in hypoxic cells of solid tumours, the use of radiation sensitisers against not only normoxic cells but also hypoxic cells is necessary in combination with radiotherapy.
Officials said the European acceptance of the principle that force might be necessary, in combination with possible critical statements about Iraq's cooperation over the next several weeks by Hans Blix, one of the chief United Nations weapons inspectors, could ultimately provide the basis for backing of force by Security Council members, including France.
In the two postpartum psychoses (Bokhari et al. 1998; Stowell and Barnhill 2005), antipsychotics were necessary in combination with thyroid treatment.
A high agitation was necessary in combination with low aeration rates to prevent blocking of the air sparger due to fungal growth.
Indications for palliative therapies include pain reduction, tumour debulking, decompression and reduction and/or prevention of impeding pathological fractures (where stabilisation will be necessary in combination with the ablation technique) [1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11].
Alternatively, additional proteins from either Chlamydia or the host cell might be necessary in combination with CtrIncA to promote fusion.
However, none of the tumors disappeared completely, with most maintaining a small volume of residual tumor, suggesting that additional drugs may be necessary in combination with mTOR inhibitors to totally ablate residual disease.
Triple therapy, the combination of aspirin, clopidogrel, and oral anticoagulation, is necessary in patients with coronary stent implantation who also have atrial fibrillation to reduce ischemic events [ 7].
His task, as he sees it, is to demonstrate that probabilistic statements are supported by a claim the "existence of a probability function"—which is a transcendental principle that is necessary, and in combination with causal principles sufficient, for empirical knowledge.
Thus, linagliptin most likely has no influence on the activity of P-glycoprotein or other transporters relevant for digoxin pharmacokinetics; therefore, dose adjustments would also not be necessary in a combination therapy with linagliptin and digoxin.
