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DND1 may be a cellular factor that is necessary for regulating some aspect of APOBEC3 activity, especially in germ cells.
Mechanical stimulation is necessary for regulating correct formation of the skeleton.
Collectively, these findings demonstrate that PP2A also regulates FOXO3a activity in CD8+ memory lymphocytes and indicate that p47phox is necessary for regulating PP2A activity.
The endosomal system is necessary for regulating, sorting and degrading proteins via autophagy or the ubiquitin proteasome system (UPS) (15).
Therefore, crosstalk between the V-ATPase and MTORC1 is necessary for regulating autophagy, and CRYBA1 is required for proper functioning of this signaling axis.
Formation of ciliary axonemal structures, such as the dynein arms, radial spokes, central pair of microtubules and central sheath, is necessary for regulating motility and beating of the cilia.
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It is logical to hypothesize that the negative regulator of PI3 kinase, PTEN, should also be necessary for regulating gastrulation cell movements in zebrafish, but no gastrulation defects was observed in zebrafish pten mutants [37].
These knowledge systems were necessary for regulating livestock grazing patterns.
The increased arrhythmicity in Kcnma1−/− recordings suggests that BK channels are necessary for regulating the day-night difference in SFR and shaping daily spontaneous activity rhythms in the SCN.
The Sp1 site, with other promoter elements such as the AP-2 site, has been shown to be necessary for regulating constitutive expression of MMP2 [28].
Thus, we conclude that the 9 nucleotides that Qrr1 lacks are necessary for regulating a subset of the Qrr targets including aphA, vibhar_00505, and vibhar_05691.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com