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It has been largely assumed in the literature that a gene whose knockout is lethal is necessarily essential for growth, but the occurrence of synthetic rescues shows that this is generally true only if no other genes are concurrently knocked out or knocked down.
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Assuming, contra Linksy and Zalta (1996), that abstractness is, necessarily, an essential feature of abstract entities, then it follows that <2+2=4> is in fact abstract.
In explaining the difference in this respect between necessity propositions and contingency propositions, he states that since the terms in per se necessity propositions are essential, 'Every A is necessarily B' and 'Whatever is necessarily A is necessarily B' mean the same.
In some ways this is Lee's most trying work — reading "On Such a Full Sea" will weed out the skimmers, as its narrative is necessarily warped to a taxing inertia essential to its story.
Experience is necessarily temporal.
Neither is necessarily right.
It is, necessarily, white.
Literature is necessarily gratuitous.
The menu is necessarily limited.
But neither is necessarily quick.
As discussed above, reactions predicted to be essential are not necessarily essential during all time points.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com