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Initial studies of investigational therapies using tumour-bearing animals should aim to determine whether the target, or an appropriate downstream pathway or phenotype, is modulated by using suitably validated pharmacodynamic biomarkers (Collins and Workman, 2006).
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An OFDM signal consists of a sum of subcarriers that are modulated by using phase shift keying (PSK) or quadrature amplitude modulation (QAM) [4].
The Mn and crosslinker content can be modulated by using a monofunctional comonomer to end-cap polymer chains.
The simulation results, obtained using a novel model including proprioceptive feedback and anatomical data, indicate that both stiffness and damping components of joint impedance may be modulated by using FES-induced co-activation of antagonist muscles.
The results demonstrated that by using the microwave-assisted hydrothermal method, the shape, size and structural phase of CePO4 can be modulated by using relatively low synthesis temperatures and short reaction times, and depending on pH, a sintering process is not needed to obtain either a desired phase or size.
The quality of the litter was modulated by using either high quality (maize leaves) or low quality materials (maize roots), and two levels of biotic complexity were tested by introducing or not introducing an ecosystem engineer (Lumbricus terrestris, anecic earthworm) into the columns.
Porcine gelatin-Ph hydrogels were found to be cytocompatible with human blood-derived endothelial colony-forming cells and white adipose tissue-derived mesenchymal stem cells, resulting in >87% viability, and cell proliferation and spreading could be modulated by using hydrogels with different proteolytic degradability and stiffness.
This can be modulated by using polymer as the carbon and nitrogen sources.
So we can set t c as the coupling between the two QDs, which can be modulated by using the gate voltages [1].
Various applications for bilayer graphene are possible due to the fact that its bandgap can be modulated by using an external out-of-plane electric field and chemical doping.
In this report, we show that the level of Twist expression can be modulated by using a pharmacological approach (i.e., a CK2 inhibitor), suggesting that CK2 could be a useful therapeutic target.
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