Sentence examples for is mediated directly from inspiring English sources

These results indicate that induction of ALKBH5 by hypoxia is mediated directly or indirectly by HIF-1α.

The inhibition is mediated directly; a single inhibitory spike is delivered to all excitatory neurons whenever any excitatory neuron spikes.

It remains to be determined whether this AMPK activation is mediated directly through the myocardial GLP-1 receptor or indirectly through improved contractile function.

This suggests that the pro-invasive effect of TNC-transfected fibroblast CM is mediated directly through secreted TNC.

Whether signaling by APF is mediated directly or indirectly by its known functional receptor CKAP4/p63 [ 58] is unknown.

However, Reelin-mediated EphB2 phosphorylation was also observed in the Dab1-deficient neurons, indicating that this effect is mediated directly via the interaction of Reelin with EphB2.

This change in insulin sensitivity is believed to be mediated directly by growth hormone binding to its receptor.

Taken together, we consider that the tissue lesion could be mediated directly by the cytotoxicity of Emuc and indirectly by the host inflammatory responses triggered by Emuc although it remains undefined to what extents the two effects of Emuc, respectively, contribute to the tissue damage.

This could have been mediated directly via NK-T cell interactions and/or NK-DC crosstalk.

Most likely, these effects are mediated directly by Aβ and not the APP holoprotein.

These ATP effects are mediated directly by P2X and P2Y receptors expressed by microglia [47].